Interim analyses, IDMCs

IDDI provides the full range of services for interim analyses and IDMCs

Interim analyses are carried out and shared with an independent body of experts (Data Safety Monitoring Board, DSMB, or Independent Data Monitoring Committee, IDMC), that guarantee that continuation of the trial remains ethically and scientifically justified.

IDDI uses several statistical techniques for interim analyses, including sequential designs, group sequential designs, adaptive designs, conditional power and futility calculations, and sample size adjustments.

Some members of the staff are dedicated solely to IDMC support. They are true experts, delivering only what the committee members need in a succinct, complete and reproducible fashion.

IDDI use its secure portal TrialControl to share reports with the IDMC members ensuring immediate access once they are posted

Client access

Over the last five years, IDDI has been involved in 60+ IDMCs as independent statistician.

14 trials in cardiovascular diseases 50500+ patients 7 trials in ophthalmology
3200+ patients
5 trials in lung cancer
2000+ patients		 2 trials in central nervous system  700+ patients
2 trials in infectious diseases
500+ patients		 1 trial study in pancreatic cancer
1000+ patients
1 trial in hepatitis C
100+ patients		 13 trials in breast cancer               
25000+ patients
8 trials in colorectal cancer
5500+ patients		 2 trials in renal cell carcinoma        1200+ patients
3 trials in GI tract
1700+ patients		 1 trial study in hepato-carcinoma  
500+ patients
1 trial in melanoma 
70+ patients		 1 trial in endocrine disease
100+ patients