DEVELOPMENT AND VALIDATION OF CLINICALLY  USEFUL GENE SIGNATURES

  Date :                 FRIDAY SEPTEMBER 3, 2010

  Time:                  04:00 PM CET - 10:00 AM EST - 07:00 AM PST

  REGISTER HERE


 

> DESCRIPTION: 

Multigene classifiers, also known simply as "gene signatures", can be developed from microarray-based expression profiling as potentially useful prognostic and/or predictive tools.
This webinar will review statistical issues in the development and validation of gene signatures.
Using three recently developed signatures (MammaPrint®, Oncotype DX® and MapQuant DxTM), we will discuss the role of gene selection, classification methods and cluster analysis in signature development, as well as the need for internal and external validation of the signatures.

> SPEAKERS:

Dr. Marc Buyse
Dr. Stefan Michiels

> KEY LEARNING OBJECTIVES:

The participants will learn:
- To understand the development and validation of gene signatures
- To identify study designs and statistical techniques appropriate for signature validation.

> WHO SHOULD ATTEND:

Statisticians and clinicians involved in the development of multigene signatures for use in the clinic.

> FEE:

No Charge.

> ADDITIONAL INFORMATION:

The webinar will last 60 min. There will be  a Q&A session at the end of the presentation. Questions can be sent to the presenter after the  presentation and answers will be in real time. Once you have registered, you will receive the instructions on how to join the parallel web and audio conference.

> SYSTEM REQUIREMENTS:

- PC-based attendees
Required: Windows® 7, Vista, XP, 2003 Server or 2000
- Macintosh®-based attendees
Required: Mac OS® X 10.4.11 (Tiger®) or newer

> REGISTER TO ATTEND:

Space is limited. If you have not registered yet, reserve your webinar seat now at: https://www1.gotomeeting.com/register/527435897. After registering you will receive a confirmation email containing information about joining the Webinar.