Our statisticians provide both fixed and dynamic randomization methods using IDDI's in-house developed web-based central randomization system (ID-net™) and its optional functionality for drug supply management (ID-supply™). So far 101 randomization systems have been implemented in 75+ countries (all continents) - 25600+ patients - 6,800+sites.
Thanks to its statistical know-how, IDDI will help you choose the most appropriate randomization methodology.
Methods such as randomly permuted blocks within strata and stochastic minimization are used to balance for prognostic factors.
To learn more about centralized randomization download 'Centralized Treatment Allocation in Comparative Clinical Trials' by Dr. Marc Buyse.
When the study drug availability is low and the expected inventory at the site is minimum, an option in ID-supply™ can be turned on to combine dynamic treatment allocation allowing partial treatment stock at the site while maintaining the expected balance for the study by using an innovative method to re-supply the sites.